At Guardian Performance Medicine, we provide evidence-based care focused on men’s health, hormone optimization, recovery, and performance. Our goal is to help patients improve energy, confidence, recovery, strength, and overall quality of life through personalized medical care and ongoing provider oversight.
Low testosterone can contribute to fatigue, low libido, decreased muscle mass, poor recovery, brain fog, and reduced motivation. We provide comprehensive evaluations, lab monitoring, and individualized treatment plans designed around your symptoms, goals, and long-term health.
Erectile dysfunction is common and often connected to underlying health concerns such as hormone imbalance, stress, vascular health, or metabolic issues. We offer discreet evaluations and personalized treatment options focused on restoring confidence and performance.
We offer medically guided hair loss treatment plans designed to help slow thinning and support healthier hair growth. Treatment options may include prescription therapies, hormone evaluation, and regenerative approaches when appropriate.
Performance starts with recovery. We help active adults and athletes manage joint pain, overuse injuries, tendonitis, mobility limitations, and recovery concerns with individualized, recovery-focused treatment plans.
Whether your goals involve improving energy, recovery, hormone balance, or overall performance, Guardian Performance Medicine delivers medically guided care built around long-term health and real results.
All treatments are prescribed only after evaluation by a licensed healthcare provider and based on medical appropriateness. Individual results may vary.
At Guardian Performance & Men’s Health, we believe in clear, upfront pricing with no hidden surprises. Most of our care is built around affordable, membership-based programs designed to give you direct access to your provider without the complexity of insurance barriers.
While some services may be eligible for insurance coverage, coverage cannot always be guaranteed depending on your plan or the specific visit type. For that reason, many patients choose our straightforward cash-based programs for consistency, simplicity, and better access to care.
Hormone optimization and men’s health programs start as low as:
$199/month
These programs are designed to support testosterone optimization, symptom improvement, lab monitoring, and ongoing clinical management.
Primary care membership options start as low as:
$63/month
These memberships include access to primary care services, chronic condition management, preventive care, and direct communication with your provider—without the typical delays and barriers of traditional insurance-based care.
At Guardian, care is built around access, clarity, and relationships—not billing complexity.

Preston Holifield, DNP, APRN, FNP-C combines evidence-based medicine with a performance-focused approach to modern healthcare. At Guardian Performance & Men’s Health, Preston works to identify and address the underlying factors contributing to fatigue, low testosterone, decreased performance, weight gain, poor recovery, sexual health concerns, and overall wellness decline.
Through collaborative medical care alongside his Missouri Licensed Collaborating Physician, Preston develops individualized treatment plans designed to optimize health, performance, confidence, and long-term wellness — not simply mask symptoms.
Preston believes men deserve healthcare that is proactive, direct, and personalized. His approach emphasizes patient education, realistic goal-setting, responsible hormone management, lifestyle optimization, and ongoing monitoring to help patients perform at their best physically, mentally, and professionally.
At Guardian, patients are treated with respect, confidentiality, and genuine care in a supportive environment where they can openly discuss their health concerns without judgment. Preston’s mission is to help patients build sustainable health, regain confidence, and become stronger, healthier versions of themselves.
Low testosterone can affect energy, libido, strength, recovery, mood, focus, and overall quality of life. We provide comprehensive evaluations and individualized treatment plans designed to safely optimize hormone levels and improve symptoms.
Erectile dysfunction is common and often linked to underlying concerns such as hormone imbalance, vascular health, stress, sleep quality, or metabolic issues. We offer discreet evaluations and personalized treatment options focused on restoring confidence and performance.
Hair loss can impact confidence at any age. We offer medically guided treatment options designed to slow progression, support healthier hair growth, and improve overall scalp and hair health.
Treatment may help:
Persistent fatigue, poor motivation, reduced stamina, and brain fog may be related to hormone imbalance, sleep issues, stress, recovery deficits, or metabolic health concerns. Our goal is to identify contributing factors and create a personalized treatment strategy.
Poor recovery, muscle loss, reduced endurance, and difficulty maintaining strength can affect both athletes and active adults. We help patients optimize recovery, mobility, and overall performance through evidence-based medical care.
We evaluate and treat common performance and recovery concerns including:
Treatment plans are focused on recovery, function, and long-term performance support.
Hormones, sleep, stress, nutrition, and metabolism all work together. We provide medically guided support for patients struggling with weight gain, poor energy, and metabolic health concerns.
Performance medicine is about more than symptoms alone. We focus on helping patients improve long-term health, confidence, recovery, and overall quality of life through proactive, individualized care.
Many patients notice improvements in energy, recovery, mood, or libido within several weeks, though results vary depending on hormone levels, lifestyle, and overall health.
Low testosterone may contribute to fatigue, low libido, erectile dysfunction, decreased muscle mass, poor recovery, brain fog, reduced motivation, and mood changes.
Yes. Comprehensive lab work and medical evaluation are required before treatment to determine if therapy is appropriate and safe.
When properly prescribed and monitored by licensed medical providers, testosterone therapy can be safe and effective for appropriate candidates. Ongoing lab monitoring is essential.
It can. Testosterone therapy may reduce fertility in some men. Your provider will discuss risks, goals, and alternative options when appropriate.
Follow-up schedules vary by treatment plan, but regular monitoring and lab review are important parts of safe hormone management.
ED can be related to hormone imbalance, stress, vascular health, medications, sleep issues, metabolic conditions, or other underlying medical concerns.
Yes. We provide confidential, professional evaluations and personalized treatment plans in a comfortable medical setting.
Treatment options may include prescription medications, hormone evaluation, lifestyle guidance, and regenerative approaches depending on the cause and severity of hair loss.
Yes. We evaluate and treat common recovery and performance concerns including joint pain, tendonitis, overuse injuries, mobility limitations, and exercise-related injuries.
Coverage varies depending on the service provided. Some performance-focused treatments may be considered elective or cash-pay services.
Absolutely. Every patient receives an individualized plan based on symptoms, labs, medical history, goals, and overall health.